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How To Use


To use the NIO patch, you just put it on your skin near where it hurts, following the path of your nerves. 

Original Nio Pain Patch

The original Nio pain patch sticks in place with two special adhesives. One is a silicone adhesive that keeps the patch on your skin. The other is a removable acrylic adhesive that sticks to the patch and can be replaced when the silicone adhesive isn't holding the patch well anymore.

Disposable Nio Pain Patch

This patch has the single adhesive that comes attached to the product. It will last you 7-10 days depending on the usage.



When To Use

For the best results, put the NIO patch on clean, dry skin after you've washed or showered. Avoid using lotions or oils on the area because they can make the adhesive less sticky, which means you might need to change it more often.

And here's the good news: the pain relief should kick in right away! Some have even mentioned feeling a nice, soothing sensation in their head when the patch is doing its job.


The NIO patch is really good at helping relieve pain. It relieves chronic pain. It can make things feel better if you have sore muscles, arthritic pain, cramps (the kind that feel like Charlie Horses), menstrual cramps, back pain, migraines, carpal tunnel syndrome, and other types of annoying chronic pain.

But, just so you know, it might not work as well for sudden, acute intense pain like what you get after surgery or a big accident. People have told us that it doesn't work great after surgeries like back, knee, shoulder, or joint replacements. If you've had a different experience, we'd love to hear about it.

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